• Access to new medications before public availability. • Close monitoring of research patients/subjects for side effects. • Contribution to advancement of treatments for similar conditions.

No. Clinical trials are not intended to replace all ongoing treatment with a primary physician. Most clinical trials provide short-term treatments related to a specific illness or condition. They do not provide extended or complete primary health care. Your health care provider will work with the research team to help ensure that the trial protocol is safe and compatible with your other medications or treatments.

Advanced Research Institute, Inc partners with pharmaceutical sponsors to conduct clinical trials aimed at improving patient health and longevity. These trials involve participants in advancing medicine, determining the effectiveness of new medications, diagnostic tools, and devices. When you participate in a clinical trial, you may: • Access to new treatments • Innovative healthcare choices • Advance medical knowledge • Assistance for similar disease or condition. Clinical research often leads to significant advances in science and medicine, with many treatments now being standard of care. Clinical trials provide opportunities to try potentially better treatments than existing ones, and when no standard treatment is available, they offer potentially effective therapies in a previously unproven setting.

A placebo is a pill or other substance that has no therapeutic effect. If a placebo is a part of a trial that you are considering, you will be full informed of that fact ahead of time.

Typically, research patients do not have any out-of-pocket expense to participate in a clinical trial. All research-related costs are covered by the pharmaceutical sponsor that is conducting the study.

• Your participation in a clinical trial can often require more time and attention than your regular health care. This could include frequent visits to the research clinic, additional treatments, outpatient procedures, or a complicated treatment regimen. • The study treatment may not work for you. • The study treatment may cause unwanted side effects.

Your participation in a clinical research study is 100% voluntary. You are able to withdraw from the study at any time, for any reason.